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Checks and prevention

The HPV vaccine in South Africa – who gets it and why

How the school-based HPV vaccination programme works, what the vaccine protects against, its safety record, and why cervical screening still matters afterwards.

What HPV is, and what the vaccine prevents

Human papillomavirus is a very common infection passed on by skin-to-skin sexual contact. Most infections clear by themselves. A few high-risk types persist, and over many years those can cause cervical cancer, as well as some cancers of the anus, penis, vulva, vagina and throat. Cervical cancer is one of the most common cancers among South African women, and it is largely preventable.

How the programme works

  • The National Department of Health runs a school-based HPV vaccination programme through public schools, at no cost.
  • Vaccination requires a signed parent or guardian consent form, which is sent home before the team visits.
  • Children who miss the school round can usually be vaccinated at a public clinic — ask at your nearest facility.
  • The vaccine is also available privately for other age groups; a clinician or pharmacist can advise on who benefits.

Safety, and what to expect on the day

  • HPV vaccines have been given to many millions of people worldwide and are among the most closely monitored vaccines in use.
  • The usual effects are a sore arm, sometimes redness or swelling, occasionally a mild headache or a low fever for a day.
  • Fainting can happen after any injection in adolescents, which is why they are asked to sit for a short while afterwards.
  • Serious allergic reactions are very rare and the vaccinating team is equipped for them.

Screening still matters

The vaccine covers the types that cause most cervical cancers, not all of them, so cervical screening remains part of routine care for women whether or not they were vaccinated. Public-sector cervical screening is available free of charge, and the schedule depends on age and HIV status — ask at your clinic what applies to you.

Common questions

Is the HPV vaccine free in South Africa?
Yes, through the National Department of Health's school-based programme in public schools, with signed parent or guardian consent. Children who miss the school round can usually be vaccinated at a public clinic.
At what age is the HPV vaccine given?
In early adolescence, through the school programme, because the immune response is strongest then and protection is greatest before any exposure to the virus. Ask your clinic which grades are covered this year.
Do I still need a Pap smear if I had the HPV vaccine?
Yes. The vaccine covers the types behind most cervical cancers but not all of them, so cervical screening stays part of routine care. Your clinic can tell you the schedule for your age and HIV status.

Sources

Last reviewed 11 August 2026.

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