Get started
Health library
Women's health

PCOS – irregular periods, weight and fertility

What polycystic ovary syndrome is, how it is diagnosed, what actually helps with periods, hair growth and weight, and its links to diabetes and fertility.

What PCOS is

Polycystic ovary syndrome is a common hormonal condition. The ovaries do not release an egg regularly, which causes irregular or absent periods, and there is often a higher level of male-type hormones, which causes extra hair growth on the face or body, acne, or thinning hair on the scalp. Many women with it also have insulin resistance, which links it to weight and to type 2 diabetes.

What helps

There is no single treatment, because the aim differs from person to person: regular periods, controlling hair or acne, reducing diabetes risk, or getting pregnant. Say which of those matters most to you — the treatment follows from the goal.

  • Weight, activity and diet have a real effect here, and a modest loss can restore ovulation in some women. This is not a brush-off; it is one of the few things that works on several symptoms at once.
  • Hormonal contraception is used to regularise periods and improve acne and unwanted hair growth in women who are not trying to conceive.
  • Metformin is used where there is insulin resistance or to reduce diabetes risk.
  • Medicines that induce ovulation are used when the goal is pregnancy.
  • Hair removal methods and acne treatment address the visible symptoms directly.

Medicines used in PCOS in South Africa, depending on the goal of treatment:

  • Metformin Glucophage, Glucophage XR, Sandoz Metformin, Adco-Metformin

    Type 2 diabetes mellitus — first-line agent

  • Levonorgestrel / Ethinylestradiol (Combined OCP) Ovral, Nordette, Triphasil, Yasmin (drospirenone/EE)

    Contraception; menstrual regulation; dysmenorrhoea; acne

  • Clomifene (Clomiphene) Clomid, Fertomid, Serophene

    Ovulation induction in anovulatory infertility; polycystic ovary syndrome (PCOS)

  • Cyproterone Acetate + Ethinylestradiol Diane-35, Ginette-35, Qlaira, Brenda-35

    Severe acne unresponsive to other treatment; hirsutism; polycystic ovary syndrome (PCOS); contraception (secondary indication)

PCOS and fertility

  • PCOS is a common cause of difficulty conceiving, and it is one of the more treatable ones.
  • Irregular ovulation does not mean no ovulation. Contraception is still needed if you do not want to become pregnant.
  • If you are trying to conceive, start folic acid before you conceive rather than after.
  • Ovulation-inducing medicines increase the chance of twins and need supervision, including monitoring. They are not something to obtain informally.

The long-term part people are not told

  • PCOS raises the risk of type 2 diabetes, including in pregnancy, so periodic glucose testing is part of care.
  • Blood pressure and cholesterol are worth checking too.
  • Depression and anxiety are more common with PCOS, partly because of the symptoms themselves. That is worth raising rather than absorbing.

Common questions

Can you get pregnant with PCOS?
Yes. PCOS is a common cause of difficulty conceiving and also one of the more treatable ones. Ovulation is irregular rather than absent, so contraception is still needed if you do not want to conceive.
Does PCOS mean I have cysts on my ovaries?
Not necessarily. The name is misleading — diagnosis rests on irregular ovulation, hormonal signs or blood tests and ultrasound together, and having cysts on a scan alone does not mean you have PCOS.
Does PCOS cause diabetes?
It raises the risk of type 2 diabetes, including diabetes in pregnancy, because insulin resistance is common with it. Periodic glucose testing is part of managing PCOS.

Sources

Last reviewed 11 August 2026.

Start growing today

Take control of your medication, one dose at a time.

Get started — it's free