Where to get PrEP in South Africa – what to ask
How to approach a South African clinic or HIV service about PrEP, which tests and follow-up matter and what to do after a possible exposure.
Start with an HIV-testing and prevention service
PrEP access begins with a confidential HIV-prevention conversation at an appropriate clinic or service. The healthcare worker checks that HIV testing is negative, asks about possible exposure and other health factors, and explains the medicine and follow-up. Availability and pathways can differ by facility, so contact the local service before travelling far.
What the first visit can cover
- HIV testing and a discussion of any recent exposure or acute symptoms.
- Sexual-health screening and prevention options such as condoms.
- Kidney, hepatitis and other checks where the guideline calls for them.
- How to take PrEP, what side effects to report and when to return.
PrEP is not a substitute for urgent PEP after an exposure. Tell the healthcare worker if an exposure has already happened.
Make the visit easier
- Call the clinic or service to ask whether it offers HIV prevention and testing.
- Take an identity or clinic card if the facility requests one, but do not delay urgent care because of paperwork.
- Bring your medicine and supplement list.
- Ask how refills, follow-up tests and privacy are handled.
After a possible exposure, go now
Common questions
- Where can I get PrEP in South Africa?
- Ask a local public clinic or HIV-testing and prevention service whether it provides PrEP and follow-up. Availability can vary, so confirm the pathway with the facility.
- What tests are needed before PrEP?
- The service will confirm HIV status and assess other health and exposure factors. It may arrange additional tests and ongoing monitoring according to the current South African guideline.
Sources
- National Consolidated Guidelines for the Management of HIV in Adults, Adolescents, Children and InfantsNational Department of Health, South Africa
- National clinical guidelines and policy libraryNational Department of Health, South Africa
Last reviewed 26 August 2026.